These instances provide data for planning problems in city logistics. The considered urban transportation system consists of two tiers and involves different modes of transportation like truck, cargo bike and public transport service. Three types of demands are considered: e2c (external to customer) demands, which require a delivery at a customer location in the inner city, c2e (customer to external) demands requiring a pickup at a customer location, and c2c (customer to customer) demands, which are shipped within the dense urban area. The instances are based on the district 'Oststadt' of Karlsruhe, a medium-size German city. The set contains 46,656 single instances, which mainly differ in the number of demands (10, 20 and 30), the modes of transport, the planning time horizon, the demand types involved, the time window widths and the maximum waiting time allowed. See the provided manual for more details.