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ZENODO
Article . 2021
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2021
License: CC BY
Data sources: Datacite
ZENODO
Article . 2021
License: CC BY
Data sources: Datacite
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Prospective Observational Study to Assess the Association between Glycemic Control, Lipid Profile and C-reactive Protein in Adults with Type 2 Diabetes Mellitus

Authors: Nilashish Dey;

Prospective Observational Study to Assess the Association between Glycemic Control, Lipid Profile and C-reactive Protein in Adults with Type 2 Diabetes Mellitus

Abstract

Aim: The aim of this study to determine the Correlation between glycemic control, lipid profile and C-reactive protein in adults with type 2 diabetes mellitus done tertiary care hospital of Jharkhand region, India. Methods: This prospective observational study was carried out in the Department of General medicine, Seikh Bhikhari Medical College, Hazaribgah, Jharkhand, India for 1 year. The patients above 28 years with fasting venous blood glucose value equal or more than 100 mg/dl and postprandial glucose >140 mg/dl were include in this study. FBS and PPBS, CRP (immunoturbidimetric method), and HbA1C (ion exchange chromatography using HPLC) lipid profile samples were drawn at entry and at subsequent follow-up with a minimum gap of 3-6 months. Results: total cholesterol was compared to CRP. Number of patients with total cholesterol 140 were 12 with mean CRP levels of 1.86, 0.85, 1.83, 0.76, 1.35, 2.28. There was no significant correlation between CRP and LDL cholesterol (p>0.05). HDL cholesterol was compared with CRP. Patients with HDL cholesterol between 0-20 were 3, between 20-40 were 43, between 40-60 were 41 and HDL cholesterol >60 were 3 with mean CRP levels of 2.15, 1.42, 1.23, 1.17, respectively. There was a negative correlation between HDL cholesterol and CRP triglyceride levels were compared with CRP. Patients with triglyceride levels between 100-200 were 45, between 200-300 were 30, between 300-400 were 8, between 400-500 was 3 and with levels >500 were 4 with mean CRP levels of 0.72, 0.85, 1.85, 2.46, 2.46, respectively. There was significant positive correlation between CRP and triglyceride levels (p10 were 33 with mean CRP of 0.48, 0.66, 1.55, 2.29, respectively. There was significant correlation between CRP and HbA1C (p<0.05). Conclusion: We concluded that the CRP is an additional marker of better glycaemic control and also correlates with the dyslipidaemia profile seen in type 2 diabetes mellitus.

Aim: The aim of this study to determine the Correlation between glycemic control, lipid profile and C-reactive protein in adults with type 2 diabetes mellitus done tertiary care hospital of Jharkhand region, India. Methods: This prospective observational study was carried out in the Department of General medicine, Seikh Bhikhari Medical College, Hazaribgah, Jharkhand, India for 1 year. The patients above 28 years with fasting venous blood glucose value equal or more than 100 mg/dl and postprandial glucose >140 mg/dl were include in this study. FBS and PPBS, CRP (immunoturbidimetric method), and HbA1C (ion exchange chromatography using HPLC) lipid profile samples were drawn at entry and at subsequent follow-up with a minimum gap of 3-6 months. Results: total cholesterol was compared to CRP. Number of patients with total cholesterol 140 were 12 with mean CRP levels of 1.86, 0.85, 1.83, 0.76, 1.35, 2.28. There was no significant correlation between CRP and LDL cholesterol (p>0.05). HDL cholesterol was compared with CRP. Patients with HDL cholesterol between 0-20 were 3, between 20-40 were 43, between 40-60 were 41 and HDL cholesterol >60 were 3 with mean CRP levels of 2.15, 1.42, 1.23, 1.17, respectively. There was a negative correlation between HDL cholesterol and CRP triglyceride levels were compared with CRP. Patients with triglyceride levels between 100-200 were 45, between 200-300 were 30, between 300-400 were 8, between 400-500 was 3 and with levels >500 were 4 with mean CRP levels of 0.72, 0.85, 1.85, 2.46, 2.46, respectively. There was significant positive correlation between CRP and triglyceride levels (p10 were 33 with mean CRP of 0.48, 0.66, 1.55, 2.29, respectively. There was significant correlation between CRP and HbA1C (p<0.05). Conclusion: We concluded that the CRP is an additional marker of better glycaemic control and also correlates with the dyslipidaemia profile seen in type 2 diabetes mellitus.

Keywords

C-reactive protein, Glycemic control, Hemoglobin A1C, Type 2 diabetes mellitus

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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