Abstarct Periodontal diseases are primarily caused by pathogenic bacteria residing in the oral cavity, contributing to inflammation and tissue destruction. The increasing incidence of antibiotic resistance has led to a growing interest in natural antibacterial agents. This study investigates the antibacterial activity of green tea (Camellia sinensis) extracts against periodontal microbes isolated from patient samples. Dental swabs were collected from patients with periodontitis, and the isolated pathogens, including Porphyromonas gingivalis, Prevotella intermedia, and Actinobacillus, were identified. The antibacterial activity of green tea extracts was evaluated using disk diffusion and minimum inhibitory concentration (MIC) assays. The results showed significant antibacterial activity of green tea extracts, with zones of inhibition comparable to those of conventional antibiotics. The green tea extracts effectively inhibited the growth of the isolated periodontal pathogens and reduced biofilm formation. These findings suggest that green tea extracts could serve as a potential adjunctive therapy in managing periodontal infections, offering a natural alternative to conventional antimicrobial treatments. Further clinical studies are needed to explore the therapeutic applications in oral health. Download Full Article.PDF DOI: https://doi.org/10.5281/zenodo.14047228 Bangladesh Journal of Dental Research & Education official publication of Bangladesh Academy of Dentistry International (BADI)® ISSN (Online): 2308-9733 ISSN (Print): 2225-9015 ZENODO@BJDRE,BADI® OpenAIRE | EXPLOR@BJDRE,BADI® ORCiD@BJDRE,BADI®