Persistent Identifiers (PIDs), such as Digital Object Identifiers (DOIs), play an essential role in creating a connected and accessible research landscape throughout Latin America. Despite the region's extensive and diverse research outputs, many repositories are not fully integrated into global registries and aggregators, which limits their visibility and reach. PID adoption varies considerably across Latin American repositories, highlighting the need to increase awareness about how open PIDs can enhance research discoverability and impact. This report reviews the current landscape of repositories and publishing systems in Latin America, along with institutional and national Open Science policies. It emphasizes the importance of collaboration among researchers, institutions, funders, librarians, and governmental bodies to close gaps in PID adoption and promote Open Science practices. By advancing these open research practices, including the strategic adoption of PIDs, Latin American research can achieve greater visibility and accessibility on a global scale. This report serves as a starting point to support local communities in building an inclusive and sustainable Open Research Infrastructure. This report is part of DataCite’s Global Access Program (GAP) activities, supported in part by grant 2022-316573 from the Chan Zuckerberg Initiative (CZI).