Background: Peripheral health workers (PHWs) can play vital roles in increasing cover- age of basic health services. Objectives: To assess the Knowledge and attitude of the PHWs on SDGs for attainment of health related goals. Design: Systematic review and Meta-analysis Methods: The literature review was systematically searched (pubMed, Medline).from studies were included this give quantitative data about knowledge and attitude for attainment of Health related goals. Results: Average sample size was 982. A pooled analysis of all studies indicated a Pooled estimate of mean age 30.42? 5 years.90% of PHWs have knowledge on general health care;>40 year age have perfect knowledge; average score of PHWs 86.71%; prevention and management (percentage agreement: 34, 20, and 19%, respectively Conclusions: This paper concludes that Peripheral health workers still do not have adequate knowledge and attitude about different conditions due to various reasons such as the limited resources available etc.