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This database contains the predictions of synergy scores between triplets of more than 100 drugs treating the cell-lines from the NCI60. Columns: NSC1: The NSC of the first drug found in the tripletNSC2: The NSC of the second drug found in the tripletNSC3: The NSC of the third drug found in the tripletCELL_NAME: The name of the treated cell-lineBliss: The synergy score (ComboScore_{1 /to 3} defined by MEAN(PREDICTED - EXPECTED_BLISS) using the best performing model. Where EXPECTED_BLISS uses the multiplicative survival principle based on the individual dose-responses against each drug in the triplet and MEAN represents the average over the different combinations of concentrations.Multi: The synergy score (ComboScore_{2 /to 3} defined by MEAN(PREDICTED - EXPECTED_MULTI) using the best performing model. Where EXPECTED_MULTI is defined as the minimum over the three possible pair-single drug combinations in the triplet, using the multiplicative survival principle.{synergy}_q{XX}: Quantile XX for the synergy aggregated over an ensemble containing 10 models
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 0 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |