This document builds on the previous versions of the Data Management Plan (hereinafter “the project DMP). It gathers the steps that were made within the project since its last review in M15. The DMP is a mandatory deliverable by the European Commission (EC) that has to be tailored to the specific project activities and should document the relevant project repositories and how they are managed. The Data Management Plan for BY-COVID is developed by WP8 as an integral part of the governance structure, and also oversees the quality assurance of the project outcomes. BY-COVID will not generate new sensitive patient level data but integrate and link pre-existing resources. Hence, responsibility remains with the original data providers, data access committees and based on processes specifically established for each dataset. The project DMP considers: Overview of the project data flow Compliance with Open Science and FAIR data sharing Ethics Requirements3, in accordance with the Grant Agreement (WP9) This document is the third version of the BY-COVID DMP delivered in month 34, being an update of the second version delivered in month 15. This deliverable is based on the template and the guidelines provided by the European Commission for the Horizon Europe Framework Programme. Of note, the project DMP has been a live document that was reviewed and updated periodically during the whole project duration.