This article examines the intricate relationship between the ancient Greek myth of Prometheus and Ridley Scott’s 2012 science fiction film Prometheus. Through a comprehensive comparative mythological analysis, the article explores how the film reimagines and modernizes the classical myth, drawing parallels between the mythological figures and the characters in the film. The study ponders the film’s portrayal of the ‘Engineers’ as contemporary analogues to the Greek gods, and how this interpretation challenges traditional notions of creation, divinity, and the human condition. Key themes such as the pursuit of knowledge, the consequences of hubris, and the nature of sacrifice are explored in both the mythological and cinematic contexts. The article also investigates the film’s treatment of technology as a double-edged sword, mirroring the gift of fire in the original myth. By analysing the black goo as a modern representation of Promethean fire, the paper highlights how the film updates ancient themes to address contemporary anxieties about technological advancement and its potential ramifications. Furthermore, the study explores how Prometheus grapples with existential questions about humanity’s origins and purpose, reflecting enduring philosophical inquiries central to the original myth. Ultimately, this article demonstrates how Scott’s Prometheus serves as a powerful vehicle for re-examining timeless themes through a contemporary lens, underscoring the continued relevance of ancient myths in helping us navigate modern existential dilemmas and ethical challenges posed by scientific progress.