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NanoString GeoMx DSP dataset from 12 primary/recurrent IDH-mutant astrocytoma samples

Research datakeyboard_double_arrow_right Dataset 05 Jan 2023Publisher:Zenodo

Authors: Van Hijfte, Levi; Geurts, Marjolein; Vallentgoed, Wies; Eilers, Paul; Sillevis Smitt, Peter; Debets, Reno; French, Pim;

doi: 10.5281/zenodo.13911761 , 10.5281/zenodo.7348326 , 10.5281/zenodo.7348325

NanoString GeoMx DSP dataset from 12 primary/recurrent IDH-mutant astrocytoma samples

- Summary
- Subjects
- Metrics

Abstract

NanoString GeoMx Digital Spatial Profiler data from 12 paired tumor resections of 6 IDH-mutant astrocytoma patients. All samples had an IDH-R132H mutation. all first resections were WHO 2016 grade II or III and second resections were WHO 2016 grade IV. The NanoString Cancer Transcriptome Atlas panel was used to measure RNA expression levels of ~1800 genes in 72 regions of interest. ROIs folder contains all images of the regions of interest used in this study, separated by tumor pairs. For information on methods see associated publication.

Related Organizations

Erasmus University Medical Center
Netherlands

Keywords

Spatial transcriptomics, IDH-mutant astrocytoma

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