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MembraneR3 Extension - a membrane elastic protein network implementation for modeling cytoskeleton

Shear-elastic protein network model in MembraneR3
Authors: Frickenhaus, Stephan;

MembraneR3 Extension - a membrane elastic protein network implementation for modeling cytoskeleton

Abstract

Abstract The lipid bilayer shape numerical model MembraneR3 (Frickenhaus, 2024) is extended with a shear-elastic network model, as basis of a membrane skeleton model. For this, local area expansion and shear stress are computed on the basis of the same spectral approach. Goal is, to reproduce qualitatively the results from Lim et. al. (2002), which simulated the transition of red blood cell membrane shape from stomatocyte to echinocyte. Here results from shear-elastic network validation simulations are prsented. References Frickenhaus, S. (2024). MembraneR3 - A spectral model of membrane shape based on Helfrich spontaneous curvature in R. Zenodo. doi: 10.5281/zenodo.13627757 Lim, H. W. G., Wortis, M., Mukhopadhyay, R. (2002) Stomatocyte-discocyte-echinocyte sequence of the human red blood cell: evidence for the bilayer- couple hypothesis from membrane mechanics. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16766-9. doi: 10.1073/pnas.202617299 ERRATUM In MembraneR3_Infra_GLS.R please remove the incomplete code of the last function LM2A( )

Keywords

Spectral Model, Shear stress, gradient filter, MembraneR3, Helfrich, UnduStick, R, Cytoskeleton, Membrane shape

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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