Background: Managing dyspnea is critical in palliative care for respiratory patients, and interdisciplinary collaboration between nurses, pharmacists, and respiratory therapists is essential for optimizing symptom control. This study explored how these professionals work together to improve symptom management in a tertiary hospital setting. Methods: A qualitative study was conducted using semi-structured interviews and focus groups with 20 healthcare professionals, including nurses, pharmacists, and respiratory therapists. Data were analyzed using thematic analysis to identify key themes related to interdisciplinary collaboration. Results: Four major themes emerged: (1) Interdisciplinary Role Clarity, highlighting the specific contributions of each profession in managing dyspnea; (2) Communication and Coordination, emphasizing the importance of regular team meetings but noting challenges with informal communication; (3) Pharmacological and Non-Pharmacological Synergy, showing the effectiveness of combining opioids, bronchodilators, and non-invasive ventilation; and (4) Challenges and Solutions in Collaborative Care, identifying workload and role overlap as barriers to optimal teamwork. Conclusion: Interdisciplinary collaboration enhances dyspnea management in palliative care patients with respiratory conditions. Clear role definitions, improved communication, and integrated pharmacological and non-pharmacological interventions are crucial for optimizing patient outcomes. Future research should explore standardized collaborative care protocols and their impact on patient outcomes.