Aim: The aim of this study was to compare the effect of the ketamine-propofol mixture (ketofol) and propofol on the insertion conditions of laryngeal mask airway in pediatrics. Methods: The Prospective Double Blind comparative study was done in the department of anesthesiology & critical care medicine IGIMS, Patna, Bihar after taking approval from institute ethical committee with CTRI Registration done: CTRI/2020/10/028242. Written informed consent was taken from each participants of the study. The Data was collected between – October 2020 to December 2021. There were total 100 patients in the study and divided into two groups with 50 each. Results: Patients under 2-14 years of age comprised the majority of study population. The P value is 0.524 and there was no statistically significant difference in the age of the patients between the two study groups. Patients under male and female comprised the majority of study population. 80% male and 20% female in Group FP and 88% male and 12% female in Group KP. Patients under ASA Grade I and II. The present study showed 94% patients in Grade I and 6% in Grade II of Group FP and 92% patients in Grade I and 8% in Grade II of Group KP. Patients of LMA size I and II. 84% patients in I and 16% in II of Group FP and 94% patients in I and 6% in II of Group KP. Swallowing/Gagging 90% patients Score 1, 6% patients score 2 and 4% score 3 of Group FP. 94 % patients Score 1, 4% patients score 2 and 2% score 3 of Group KP. The P. value is significant. (P = 0.001). Conclusion: In this study, I conclude that co-induction with Ketamine (1 mg/kg) and Propofol (2.5 mg/kg) for insertion of Laryngeal Mask Airway in children provided better insertion conditions and minimal alteration in haemodynamic parameters than co-induction with Fentanyl (1μg/kg) and Propofol (2.5 mg/kg).

Aim: The aim of this study was to compare the effect of the ketamine-propofol mixture (ketofol) and propofol on the insertion conditions of laryngeal mask airway in pediatrics. Methods: The Prospective Double Blind comparative study was done in the department of anesthesiology & critical care medicine IGIMS, Patna, Bihar after taking approval from institute ethical committee with CTRI Registration done: CTRI/2020/10/028242. Written informed consent was taken from each participants of the study. The Data was collected between – October 2020 to December 2021. There were total 100 patients in the study and divided into two groups with 50 each. Results: Patients under 2-14 years of age comprised the majority of study population. The P value is 0.524 and there was no statistically significant difference in the age of the patients between the two study groups. Patients under male and female comprised the majority of study population. 80% male and 20% female in Group FP and 88% male and 12% female in Group KP. Patients under ASA Grade I and II. The present study showed 94% patients in Grade I and 6% in Grade II of Group FP and 92% patients in Grade I and 8% in Grade II of Group KP. Patients of LMA size I and II. 84% patients in I and 16% in II of Group FP and 94% patients in I and 6% in II of Group KP. Swallowing/Gagging 90% patients Score 1, 6% patients score 2 and 4% score 3 of Group FP. 94 % patients Score 1, 4% patients score 2 and 2% score 3 of Group KP. The P. value is significant. (P = 0.001). Conclusion: In this study, I conclude that co-induction with Ketamine (1 mg/kg) and Propofol (2.5 mg/kg) for insertion of Laryngeal Mask Airway in children provided better insertion conditions and minimal alteration in haemodynamic parameters than co-induction with Fentanyl (1μg/kg) and Propofol (2.5 mg/kg).