Background: Both the mother and the foetus experience significant physiological stress throughout pregnancy. There is a significant risk of unfavourable outcomes for both the mother and the foetus when endocrine abnormalities like hypothyroidism are present during pregnancy. All pregnant women should be screened for subclinical hypothyroidism, especially in the Indian context where there is a higher risk of iodine deficit during pregnancy. Therefore, the purpose of this study was to determine how subclinical hypothyroidism affected the course of pregnancy. Method: A prospective analytical study was conducted at SKMCH, Muzaffarpur, Bihar from April 2022 to September 2022. The sample size was made up of 73 expectant women who visited the prenatal OPD. During the initial appointment, a thyroid profile (serum TSH, FT3 and FT4) was performed. TSH >2.5mIU/L in the first trimester, >3mIU/L in the second trimester, and >3.5mIU/L in the third trimester were the cutoff values used by the SCH to assess the findings. Information was recorded about the participants’ general characteristics. The participants checked in to assess the delivery method, the mother’s and fetus’s health, and any co-morbid conditions that might have developed. Women with SCH are treated as such. Results: Thyroid screening was done on 73 pregnant women, and 24.7% of them showed subclinical hypothyroidism. In contrast to 72.3% of euthyroid women, 55.6% of SCH women were under the age of 25. For iodized salt consumption, food type, and BMI, there was no discernible difference between the SCH and euthyroid groups (p>0.05). SCH was linked to increased incidences of elevated blood pressure (27.8% vs 7.3%, p=0.02) and low birth weight (38.9% vs 14.5%, p=0.03) in infants compared to euthyroid condition. In contrast to euthyroid women, the proportion of SCH women with anaemia and a low APGAR score was also higher. The significance was merely somewhat high. (Poor APGAR score: 27.8% vs. 9.1%; Anaemia: 72.2% vs. 45.5%, p=0.049). Conclusion: Indians have a rather high prevalence of subclinical hypothyroidism among pregnant women. Unfavourable maternal and foetal outcomes were observed in pregnant women with SCH, with a higher risk of high blood pressure and low birth weight neonates. In order to improve maternal and perinatal outcomes, routine maternal thyroid function testing is required.

Background: Both the mother and the foetus experience significant physiological stress throughout pregnancy. There is a significant risk of unfavourable outcomes for both the mother and the foetus when endocrine abnormalities like hypothyroidism are present during pregnancy. All pregnant women should be screened for subclinical hypothyroidism, especially in the Indian context where there is a higher risk of iodine deficit during pregnancy. Therefore, the purpose of this study was to determine how subclinical hypothyroidism affected the course of pregnancy. Method: A prospective analytical study was conducted at SKMCH, Muzaffarpur, Bihar from April 2022 to September 2022. The sample size was made up of 73 expectant women who visited the prenatal OPD. During the initial appointment, a thyroid profile (serum TSH, FT3 and FT4) was performed. TSH >2.5mIU/L in the first trimester, >3mIU/L in the second trimester, and >3.5mIU/L in the third trimester were the cutoff values used by the SCH to assess the findings. Information was recorded about the participants’ general characteristics. The participants checked in to assess the delivery method, the mother’s and fetus’s health, and any co-morbid conditions that might have developed. Women with SCH are treated as such. Results: Thyroid screening was done on 73 pregnant women, and 24.7% of them showed subclinical hypothyroidism. In contrast to 72.3% of euthyroid women, 55.6% of SCH women were under the age of 25. For iodized salt consumption, food type, and BMI, there was no discernible difference between the SCH and euthyroid groups (p>0.05). SCH was linked to increased incidences of elevated blood pressure (27.8% vs 7.3%, p=0.02) and low birth weight (38.9% vs 14.5%, p=0.03) in infants compared to euthyroid condition. In contrast to euthyroid women, the proportion of SCH women with anaemia and a low APGAR score was also higher. The significance was merely somewhat high. (Poor APGAR score: 27.8% vs. 9.1%; Anaemia: 72.2% vs. 45.5%, p=0.049). Conclusion: Indians have a rather high prevalence of subclinical hypothyroidism among pregnant women. Unfavourable maternal and foetal outcomes were observed in pregnant women with SCH, with a higher risk of high blood pressure and low birth weight neonates. In order to improve maternal and perinatal outcomes, routine maternal thyroid function testing is required.