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The dataset contains GWAS summary statistics for 2,083 plasma circulating microRNAs, obtained from nearly 2,178 participants of the Rotterdam Study. The dataset includes three files, as outlined below: File1: SNP_reference_file_maf0.01_Rsq0.7.txt A reference file for SNPs with good imputation quality (Rsq > 0.7) and minor allele frequency > 0.01 among participants included in our GWAS in the Rotterdam Study (N=2,178). The headers are: SNP: rsID chr: chromosome number according to GRCh37 bp: basepair position according to GRCh37 effect_allele: effect allele other_allele: other allele eaf: effect allele frequency File2: miReQTLs_1e-5_maf0.01_Rsq0.7.txt Summary statistics for all SNPs significantly associated with 2083 miRNAs (p-value 0.01 and Rsq > 0.7. The headers are: SNP: rsID beta: effect estimate se: standard error pval: p-value miRNA: miRNA ID File3: miReQTLs_nominal_sig.csv.gz Summary statistics for all SNPs nominally associated with 2083 miRNAs (p-value < 0.05). The headers are: RSID: SNP ID p-value: p-value phenotype: miRNA SE: standard error BETA: effect estimate The SNP allelic information and frequency can be found in the reference file (File1). For more information, please contact: m.ghanbari@erasmusmc.nl
microRNA, GWAS, Plasma cell-free miRNAs, miRNA-eQTL, Population study
microRNA, GWAS, Plasma cell-free miRNAs, miRNA-eQTL, Population study
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