We present preliminary results based on a homogeneous analysis of the DEep Spectra of Ionized REgions Database (DESIRED), a compilation of high signal-to-noise ratio optical spectra of photoionized nebulae. The database comprises more than 1800 spectra of Galactic and extragalactic HII regions and H II galaxies, and more than 200 spectra of planetary nebulae (PNe), as well as other photoionized nebulae such as ring nebulae or Herbig-Haro objects. The analysis of a first reduced version (190 objects) of this database has revealed important implications for various astrophysical problems, such as the presence of temperature fluctuations to explain the abundance discrepancy problem in HII regions (Méndez-Delgado et al. 2023a), or the effects of electron density inhomogeneities on the temperature structure of the nebulae (Méndez-Delgado et al. 2023b). In this poster, we focus on the potential of DESIRED to address some open problems in chemical abundances in PNe.