Identification of MAPK1 Inhibitors from Blumea oxyodonta and Cardiospermum halicacabum for Colorectal Cancer
Identification of MAPK1 Inhibitors from Blumea oxyodonta and Cardiospermum halicacabum for Colorectal Cancer
Abstract: Colorectal cancer is significant health concern worldwide. Mitogen-activated protein kinase 1 (MAPK1) is a critical therapeutic target for this malignancy. Natural compounds have potency for different type of cancers due to their diverse structures. Compounds selected for this study were taken from Blumea oxyodonta and Cardiospermum halicacabum. Computational docking analysis revealed promising binding affinities of some of these compounds to MAPK1, suggesting their potential as lead molecules for developing novel therapeutic interventions against colorectal cancer.
Keywords: MAPK1, Colorectal cancer, Blumea oxyodonta, Cardiospermum halicacabum, molecular docking
Keywords: MAPK1, Colorectal cancer, Blumea oxyodonta, Cardiospermum halicacabum, molecular docking
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!