Abstract The world is facing unprecedented change. The knowledge economy appears and brings many influences to the development of countries and peoples, but also poses many difficulties and challenges. For Vietnam, the knowledge economy opens up great opportunities in the process of promoting industrialization and modernization of the country. Developing human resources in general and high-quality human resources in particular has become even more important. and urgent for the country building process. Within the scope of this article, the author points out high-quality human resources in Vietnam, thereby offering some solutions to develop high-quality human resources in the context of today's development of the knowledge economy. Keywords: Human resources, high quality, knowledge economy.