Australian BioCommons supplies national bioinformatics research infrastructure to enhance research into the molecular basis of life across all life sciences, including environmental, agricultural, and biomedical science. It is the bioinformatics component of Bioplatforms Australia’s research infrastructure platforms and was established by Bioplatforms Australia in 2019. This document summarises the mission, organisational design and implementation methodology of Australian BioCommons during the 2023-28 period.