Background: Among the hemoglobin disorders Thalassemia is considered as the frequently encountered disorder all over the world. Studies on clinical spectrum are varying. Aim of the study: To record the population prevalence and spectrum of thalassemia diseases. The objectives were to observe the epidemiological and social factors of this disease. Materials: Prospective and descriptive study for two years in a tertiary care Hospital included 71 Thalassemia children between 02 to 15 years. Interview with formulated questionnaire proforma consisting of social and demographic variables was used. Children given blood transfusion 08 years after and 08 years before diagnosis were grouped as A &B. Variables used: BMI, Hb, MCV, MCH and RDW-CV levels, Hb chromatogram: (HbA2 and Hb F levels) and spleen size. Results: Among 71 children 44 (61.97%) males and 27 (38.02%) were female. 77.46% of the total children belonged to below 5 years to 11 years. The mean age was 07.32±2.85 years. The mean age of diagnosis of Thalassemia was 2.36±2.05 years. 60.56% children were from rural background and 39.43% from urban. 22.53% children belonged to upper class of social status, 49.29% belonged to middle class and 20 (28.16%) of children belonged to lower social class. Conclusion: The incidence of Thalassemia was in concurrence with the national figures. >75% children were diagnosed before 11 years. Commencement of blood transfusions was not significant as the BMI and hematology profiles were same in all the children.

Background: Among the hemoglobin disorders Thalassemia is considered as the frequently encountered disorder all over the world. Studies on clinical spectrum are varying. Aim of the study: To record the population prevalence and spectrum of thalassemia diseases. The objectives were to observe the epidemiological and social factors of this disease. Materials: Prospective and descriptive study for two years in a tertiary care Hospital included 71 Thalassemia children between 02 to 15 years. Interview with formulated questionnaire proforma consisting of social and demographic variables was used. Children given blood transfusion 08 years after and 08 years before diagnosis were grouped as A &B. Variables used: BMI, Hb, MCV, MCH and RDW-CV levels, Hb chromatogram: (HbA2 and Hb F levels) and spleen size. Results: Among 71 children 44 (61.97%) males and 27 (38.02%) were female. 77.46% of the total children belonged to below 5 years to 11 years. The mean age was 07.32±2.85 years. The mean age of diagnosis of Thalassemia was 2.36±2.05 years. 60.56% children were from rural background and 39.43% from urban. 22.53% children belonged to upper class of social status, 49.29% belonged to middle class and 20 (28.16%) of children belonged to lower social class. Conclusion: The incidence of Thalassemia was in concurrence with the national figures. >75% children were diagnosed before 11 years. Commencement of blood transfusions was not significant as the BMI and hematology profiles were same in all the children.