Aim: The aim of the study to assess the prevalence and severity of vitamin D insufficiency in type 2 DM patients and to know whether any correlation between level of glycemic control and vitamin D insufficiency. Methods: A case-control study was conducted in the Department of General Medicine, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna, Bihar, India. Total 200 participants were included in the study, out of which 100 type 2 diabetic patients were included as case (Group A) and 100 healthy people as controls (Group B). Routine laboratory Investigations like CBC, FBS, RBS, PP2BS, HbA1C, blood urea, serum creatinine, lipid profile, urine albumin and Vitamin D3 levels were done by standard methods in central laboratory of Institute. Results: In the study population, the mean age of group A (case) was 50.58±10.55 years while that of group B (control) was 48.82±10.36 years. Total 110 males and 90 females were enrolled in study. 66% of group A were male and 34% female. Group B (control) had 46% males and 54 females. Prevalence of low vitamin D level in healthy population was only 24 % in my study, while prevalence was 85 % in Diabetic group. Among diabetic patients having abnormal Vitamin D level, majority 67%) were having insufficiency, only 18% were having overt vitamin D deficiency in Diabetic patients. In patients with controlled diabetes as per HbA1C criteria, the prevalence of sufficient, Insufficient and Deficient Vitamin D was 20.45%, 65.91% and 13.64% respectively, where in patients with uncontrolled diabetes it was 7.14%, 75% and 17.86% respectively. More number of diabetic patients with uncontrolled status (17.86%) were having overt vitamin D deficiency in comparison to controlled status (13.64%). Hypertension was most common co-morbidity found in diabetic group (12%) followed by ischemic heart disease (7%). Serum vitamin D level was measured in all participants. 85 of diabetic population was having less than normal vitamin D level, while only 24% had less than normal vitamin D level in group B (control). Mean value of vitamin D in type 2 Diabetic patients was 28.83±6.97 ng/dl and mean value of vitamin D in healthy individuals was 37.21±4.89 ng/dl. Conclusion: We concluded that the control of diabetic status is mandatory in order to prevent vitamin D deficiency.

Aim: The aim of the study to assess the prevalence and severity of vitamin D insufficiency in type 2 DM patients and to know whether any correlation between level of glycemic control and vitamin D insufficiency. Methods: A case-control study was conducted in the Department of General Medicine, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna, Bihar, India. Total 200 participants were included in the study, out of which 100 type 2 diabetic patients were included as case (Group A) and 100 healthy people as controls (Group B). Routine laboratory Investigations like CBC, FBS, RBS, PP2BS, HbA1C, blood urea, serum creatinine, lipid profile, urine albumin and Vitamin D3 levels were done by standard methods in central laboratory of Institute. Results: In the study population, the mean age of group A (case) was 50.58±10.55 years while that of group B (control) was 48.82±10.36 years. Total 110 males and 90 females were enrolled in study. 66% of group A were male and 34% female. Group B (control) had 46% males and 54 females. Prevalence of low vitamin D level in healthy population was only 24 % in my study, while prevalence was 85 % in Diabetic group. Among diabetic patients having abnormal Vitamin D level, majority 67%) were having insufficiency, only 18% were having overt vitamin D deficiency in Diabetic patients. In patients with controlled diabetes as per HbA1C criteria, the prevalence of sufficient, Insufficient and Deficient Vitamin D was 20.45%, 65.91% and 13.64% respectively, where in patients with uncontrolled diabetes it was 7.14%, 75% and 17.86% respectively. More number of diabetic patients with uncontrolled status (17.86%) were having overt vitamin D deficiency in comparison to controlled status (13.64%). Hypertension was most common co-morbidity found in diabetic group (12%) followed by ischemic heart disease (7%). Serum vitamin D level was measured in all participants. 85 of diabetic population was having less than normal vitamin D level, while only 24% had less than normal vitamin D level in group B (control). Mean value of vitamin D in type 2 Diabetic patients was 28.83±6.97 ng/dl and mean value of vitamin D in healthy individuals was 37.21±4.89 ng/dl. Conclusion: We concluded that the control of diabetic status is mandatory in order to prevent vitamin D deficiency.