Background: Epidural anesthesia is a widely used technique for lower limb surgeries, providing effective pain control and facilitating faster recovery. Levobupivacaine and Ropivacaine are two commonly used local anesthetics for this purpose, each with distinct pharmacological profiles. While both agents offer benefits in terms of efficacy and safety, their comparative performance in clinical practice warrants further investigation. Aim: To compare the effects of epidural Levobupivacaine 0.5% and Ropivacaine 0.75% in patients undergoing lower limb surgeries. Methods: The study involved 96 patients scheduled for elective lower limb surgeries. Participants were randomly assigned to receive either Levobupivacaine 0.5% (20 ml) or Ropivacaine 0.75% (20 ml) epidurally. Data on the onset and duration of sensory block, hemodynamic parameters, adverse effects, and patient satisfaction were collected and analyzed using SPSS version 23.0. Results: Ropivacaine demonstrated a significantly faster onset of sensory block (8.7 ± 2.1 minutes) compared to Levobupivacaine (11.2 ± 2.5 minutes, p < 0.001). The duration of analgesia was also longer with Ropivacaine (292.8 ± 34.9 minutes) than with Levobupivacaine (245.4 ± 32.7 minutes, p < 0.001). Both groups exhibited stable hemodynamic profiles and minimal adverse effects, with no significant differences between the two. Patient satisfaction was slightly higher in the Ropivacaine group, although not statistically significant. Conclusion: Ropivacaine 0.75% offers advantages over Levobupivacaine 0.5% in terms of a faster onset and longer duration of analgesia, making it a preferable choice for epidural anesthesia in lower limb surgeries. Both anesthetics are safe and effective, but Ropivacaine may enhance patient satisfaction due to its prolonged analgesic effect. Recommendations: Based on these findings, Ropivacaine should be considered as a first-line epidural anesthetic in lower limb surgeries, particularly in cases where rapid onset and extended duration are critical.

Background: Epidural anesthesia is a widely used technique for lower limb surgeries, providing effective pain control and facilitating faster recovery. Levobupivacaine and Ropivacaine are two commonly used local anesthetics for this purpose, each with distinct pharmacological profiles. While both agents offer benefits in terms of efficacy and safety, their comparative performance in clinical practice warrants further investigation. Aim: To compare the effects of epidural Levobupivacaine 0.5% and Ropivacaine 0.75% in patients undergoing lower limb surgeries. Methods: The study involved 96 patients scheduled for elective lower limb surgeries. Participants were randomly assigned to receive either Levobupivacaine 0.5% (20 ml) or Ropivacaine 0.75% (20 ml) epidurally. Data on the onset and duration of sensory block, hemodynamic parameters, adverse effects, and patient satisfaction were collected and analyzed using SPSS version 23.0. Results: Ropivacaine demonstrated a significantly faster onset of sensory block (8.7 ± 2.1 minutes) compared to Levobupivacaine (11.2 ± 2.5 minutes, p < 0.001). The duration of analgesia was also longer with Ropivacaine (292.8 ± 34.9 minutes) than with Levobupivacaine (245.4 ± 32.7 minutes, p < 0.001). Both groups exhibited stable hemodynamic profiles and minimal adverse effects, with no significant differences between the two. Patient satisfaction was slightly higher in the Ropivacaine group, although not statistically significant. Conclusion: Ropivacaine 0.75% offers advantages over Levobupivacaine 0.5% in terms of a faster onset and longer duration of analgesia, making it a preferable choice for epidural anesthesia in lower limb surgeries. Both anesthetics are safe and effective, but Ropivacaine may enhance patient satisfaction due to its prolonged analgesic effect. Recommendations: Based on these findings, Ropivacaine should be considered as a first-line epidural anesthetic in lower limb surgeries, particularly in cases where rapid onset and extended duration are critical.