Pawlicka Marta, Fałkowska Urszula, Bałabuszek Kamil, Radzka Agnieszka, Mroczek Anna, Bednarski Jerzy. Vitamin D and hypertension. Journal of Education, Health and Sport. 2018;8(9):219-228. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1346149 http://ojs.ukw.edu.pl/index.php/johs/article/view/5823 https://pbn.nauka.gov.pl/sedno-webapp/works/873793 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eissn 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.06.2018. Revised: 18.06.2018. Accepted: 16.08.2018. Vitamin D and hypertension Marta Pawlicka1, Urszula Fałkowska1, Kamil Bałabuszek1, Agnieszka Radzka1, Anna Mroczek1, Jerzy Bednarski2 1 Student Research Circle at the Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, Poland 2 Department of Human Anatomy, Chair of Human Anatomy, Medical University of Lublin, Poland ORCID ID Marta Pawlicka https://orcid.org/0000-0002-6631-979X Urszula Fałkowska https://orcid.org/0000-0002-8561-8904 Kamil Bałabuszek https://orcid.org/0000-0002-1352-153X Agnieszka Radzka https://orcid.org/0000-0002-3484-4602 Anna Mroczek https://orcid.org/0000-0003-0077-5343 Jerzy Bednarski https://orcid.org/0000-0002-0186-3268 Abstract Introduction: Current epidemiological studies indicate, that insufficiency of vitamin D affects 50% of the population worldwide. 1α,25(OH)2D – active form of vitamin D affects tissues and organs through vitamin D receptor (VDR). Attention to the role of vitamin D deficiency in hypertension development has been continuously increased during recent decades. The aim of the study: The purpose of this narrative systemic review was to analyse and summarize available data on role of vitamin D deficiency in hypertension development. Material and method: Standard criteria were used to review the literature data. The search of articles in the PubMed and Google Scholar database was carried out using the following keywords: hypertension, calcitriol, vitamin D, 25-hydroxyvitamin D. Description of the state of knowledge: Vitamin D influence blood pressure level through renin-angiotensin-aldosterone system (RAAS) and parathormone regulation. Studies conducted on animal model could explain possible mechanism of vitamin D influence on blood pressure control. However, clinical trial results are equivocal due to differences in sample size, heterogeneity of patient baseline characteristics, different vitamin D doses and study duration. Summary: Further research is needed to confirm the role of vitamin D in hypertension development. Key words: vitamin D, hypertension, blood pressure, cholecalciferol