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Infection, Genetics and Evolution
Article . 2016 . Peer-reviewed
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Article . 2016
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ZENODO
Article . 2016
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ZENODO
Article . 2016
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Sequencing and molecular modeling identifies candidate members of Caliciviridae family in bats

Authors: Kemenesi, Gábor; Gellért, Ákos; Dallos, Bianka; Görföl, Tamás; Boldogh, Sándor; Estók, Péter; Marton, Szilvia; +4 Authors

Sequencing and molecular modeling identifies candidate members of Caliciviridae family in bats

Abstract

(Uploaded by Plazi for the Bat Literature Project) Emerging viral diseases represent an ongoing challenge for globalized world and bats constitute an immense, partially explored, reservoir of potentially zoonotic viruses. Caliciviruses are important human and animal pathogens and, as observed for human noroviruses, they may impact on human health on a global scale. By screening fecal samples of bats in Hungary, calicivirus RNA was identified in the samples of Myotis daubentonii and Eptesicus serotinus bats. In order to characterize more in detail the bat caliciviruses, large portions of the genome sequence of the viruses were determined. Phylogenetic analyses and molecular modeling identified firmly the two viruses as candidate members within the Caliciviridae family, with one calicivirus strain resembling members of the Sapovirus genus and the other bat calicivirus being more related to porcine caliciviruses of the proposed genus Valovirus. This data serves the effort for detecting reservoir hosts for potential emerging viruses and recognize important evolutionary relationships.

Countries
Hungary, Italy
Keywords

Behavior and Systematic, Microbiology (medical), Models, Molecular, Protein Conformation, alpha-Helical, Evolution, Short Communication, bats, Serotine bat, Gene Expression, bat, Genome, Viral, SV Veterinary science / állatorvostudomány, Microbiology, QR355 Virology / víruskutatás, Feces, Genetic, Chiroptera, Animals, Humans, Animalia, Amino Acid Sequence, Chordata, Molecular Biology, Caliciviru, Phylogeny, Caliciviridae Infections, Disease Reservoirs, Hungary, Ecology, Sequence Homology, Amino Acid, Viru, Bat, High-Throughput Nucleotide Sequencing, Daubenton's bat, Biodiversity, Europe, Infectious Diseases, Mammalia, RNA, Viral, Capsid Proteins, Protein Conformation, beta-Strand, Protein modeling, Caliciviridae, Sequence Alignment

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    15
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
15
Top 10%
Average
Top 10%
Green
gold