
Background: The liver being a multifunctional organ with major function of various metabolisms, it is strongly dependent on hepato-cardiac vascular connection. Objectives: To study the relationship between liver function test (LFT) and severity of congestive heart failure (CHF) and to correlate the functioning of liver with etiology of CHF patients. Materials and Methods: This prospective observational study was conducted in General Medicine department of tertiary care teaching hospital of Udaipur, Rajasthan. All patient aged 18-65 years with CHF of any aetiology were included. Serum bilirubin, serum SGOT and SGPT, serum ALP, serum proteins and prothrombin time was measured in all the patients and these were correlated with the severity of cardiac disease. Results: There was significant rise in mean serum ALT level, AST level, prothrombin time and bilirubin level with advancement of heart failure severity and were found highest in NYHA class IV. (p0.05). Conclusion: This study concluded that LFTs were significantly elevated in NYHA class IV of heart failure as compared to NYHA class I and LFTs showed significant correlation with severity of heart failure (NYHA class). Early and timely management of congestive heart failure will improve LFTs and will prevent significant liver failure.
Background: The liver being a multifunctional organ with major function of various metabolisms, it is strongly dependent on hepato-cardiac vascular connection. Objectives: To study the relationship between liver function test (LFT) and severity of congestive heart failure (CHF) and to correlate the functioning of liver with etiology of CHF patients. Materials and Methods: This prospective observational study was conducted in General Medicine department of tertiary care teaching hospital of Udaipur, Rajasthan. All patient aged 18-65 years with CHF of any aetiology were included. Serum bilirubin, serum SGOT and SGPT, serum ALP, serum proteins and prothrombin time was measured in all the patients and these were correlated with the severity of cardiac disease. Results: There was significant rise in mean serum ALT level, AST level, prothrombin time and bilirubin level with advancement of heart failure severity and were found highest in NYHA class IV. (p0.05). Conclusion: This study concluded that LFTs were significantly elevated in NYHA class IV of heart failure as compared to NYHA class I and LFTs showed significant correlation with severity of heart failure (NYHA class). Early and timely management of congestive heart failure will improve LFTs and will prevent significant liver failure.
Congestive Heart Failure, Liver Function Test, NYHA Class
Congestive Heart Failure, Liver Function Test, NYHA Class
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