Sugarcane bagasse is a rich source of cellulose, hemicellulose, lignin, and some other extracts. Sugarcane bagasse generated in very high amounts has been a big issue for industries and the environment globally for the past few years. Therefore, proper pretreatment is important to efficiently solubilize the lignin that shows cellulose and hemicellulose for various enzymatic actions. Pretreatment decreases the biomass i.e., the crystallinity of cellulose, structural complexity of cell wall, and lignification process for its effective use in biorefinery. The present research describes the utility of sugarcane bagasse as a sustainable and renewable cellulose substrate for the production of industrially important multifarious value-added excipients i.e. Micro Crystalline Cellulose.