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ZENODO
Dataset . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Dataset . 2024
License: CC BY
Data sources: Datacite
ZENODO
Dataset . 2024
License: CC BY
Data sources: Datacite
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Large-scale UK Biobank Whole Body Atlases

Authors: Starck, Sophie; Sideri-Lampretsa, Vasiliki; Ritter, Jessica J. M.; Zimmer, Veronika; Braren, Rickmer; Mueller, Tamara T.; Rueckert, Daniel;

Large-scale UK Biobank Whole Body Atlases

Abstract

Population atlases are commonly utilised in medical imaging to facilitate the investigation of variability across populations. Such atlases enable the mapping of medical images into a common coordinate system, promoting comparability and enabling the study of inter-subject differences. Constructing such atlases becomes particularly challenging when working with highly heterogeneous datasets, such as whole-body images, where subjects show significant anatomical variations.In this work, we propose a pipeline for generating a standardised whole-body atlas for a highly heterogeneous population by partitioning the population into anatomically meaningful subgroups. Using magnetic resonance (MR) images from the UK Biobank dataset, we create six whole-body atlases representing a healthy population average. We furthermore unbias them, and this way obtain a realistic representation of the population.In addition to the anatomical atlases, we generate probabilistic atlases that capture the distributions of abdominal fat (visceral and subcutaneous) and five abdominal organs across the population (liver, spleen, pancreas, left and right kidneys).We demonstrate a clinical application of these atlases, using the differences between subjects with medical conditions such as diabetes and cardiovascular diseases and healthy subjects from the atlas space.With this work, we make the constructed anatomical and label atlases publically available and anticipate them to support medical research conducted on whole-body MR images.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average