Introduction: Surgical Site Infections could involve an organ or bodily space, a shallow or deep incisional infection, or both. The third most frequently reported nosocomial infection in the hospital population, postoperative SSI is one of the most frequent issues for patients, who receive cesarean sections. The prevalence of postoperative SSI varies significantly across procedures, hospitals, doctors, patients, and geographical locales. It makes things more difficult worldwide including Ethiopia (21%), India (2.85%), and Nigeria (7-9.6%). Aims and Objectives: To analyze the efficacy in terms of sensitivity and resistance of various antibiotics in the management of surgical site infection with respect to the causal organisms. Methods: This is a prospective study conducted on 430 patients. In addition, out of 430 patients were operated on for clean surgeries, clean-contaminated surgeries, contaminated surgeries. The postoperative wound discharge was collected and bacterial pathogens were isolated. The plates were incubated at 37°C overnight for 24-48 hours. A hand lens was used whenever necessary to inspect all plate cultures. Results: The study found that a total of 430 patients were studied for the development of Post-Operative Surgical Site Infection. It has been found that 32 out of 430 cases showed growth of 36 isolates, with overall post-operative surgical site infection rate of 7.47%. The study found 100% resistance is present in Klebsiella, E. coli with ampicillin while amikacin and gentamicin have 100% resistance with Acinetobacter. Conclusion: The study has shown sensitivity and resistance of different antibiotics with different micro-organisms and have brought forward an image of epidemiological view of surgical site infection, all of which, would contribute in the postoperative management efficiently.

Introduction: Surgical Site Infections could involve an organ or bodily space, a shallow or deep incisional infection, or both. The third most frequently reported nosocomial infection in the hospital population, postoperative SSI is one of the most frequent issues for patients, who receive cesarean sections. The prevalence of postoperative SSI varies significantly across procedures, hospitals, doctors, patients, and geographical locales. It makes things more difficult worldwide including Ethiopia (21%), India (2.85%), and Nigeria (7-9.6%). Aims and Objectives: To analyze the efficacy in terms of sensitivity and resistance of various antibiotics in the management of surgical site infection with respect to the causal organisms. Methods: This is a prospective study conducted on 430 patients. In addition, out of 430 patients were operated on for clean surgeries, clean-contaminated surgeries, contaminated surgeries. The postoperative wound discharge was collected and bacterial pathogens were isolated. The plates were incubated at 37°C overnight for 24-48 hours. A hand lens was used whenever necessary to inspect all plate cultures. Results: The study found that a total of 430 patients were studied for the development of Post-Operative Surgical Site Infection. It has been found that 32 out of 430 cases showed growth of 36 isolates, with overall post-operative surgical site infection rate of 7.47%. The study found 100% resistance is present in Klebsiella, E. coli with ampicillin while amikacin and gentamicin have 100% resistance with Acinetobacter. Conclusion: The study has shown sensitivity and resistance of different antibiotics with different micro-organisms and have brought forward an image of epidemiological view of surgical site infection, all of which, would contribute in the postoperative management efficiently.