Prylińska M., Husejko J., Skierkowska N., Bieniek D., Kożuchowski M., Porada M., Topka W., Modrzejewski M., Wąsicki M., Wysocka O., Kędziora-Kornatowska K. Nutritional and dietary interventions for the treatment of Chronic Fatigue Syndrome. Journal of Education, Health and Sport. 2018;8(8):265-280. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1307482 http://ojs.ukw.edu.pl/index.php/johs/article/view/5639 https://pbn.nauka.gov.pl/sedno-webapp/works/869909 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 25.06.2018. Revised: 28.06.2018. Accepted: 08.07.2018. Nutritional and dietary interventions for the treatment of Chronic Fatigue Syndrome M. Prylińska1, J. Husejko1, N. Skierkowska1, D. Bieniek1, M. Kożuchowski1, M. Porada1, W. Topka1, M. Modrzejewski1, M. Wąsicki1, O. Wysocka1, K. Kędziora-Kornatowska1 Faculty of Health Sciences, Department and Clinic of Geriatrics, Nicolaus Copernicus University M. Prylińska MD1, J. Husejko1, N. Skierkowska1, D. Bieniek1, M. Kożuchowski MD1, M. Porada1, W. Topka1, M. Modrzejewski1, M. Wąsicki1, O. Wysocka1, K. Kędziora-Kornatowska1 Abstract Background: Chronic fatigue syndrome is an increasingly frequent disorder characterized by prolonged fatigue and few specific symptoms. He favors prolonged stress and life in a constant hurry. The main symptoms of chronic fatigue include: headache, throat, myalgia, joint pain, short-term memory impairment, sleep disorders, malaise occurring after physical exertion and lasting over 24 hours, and painful lymph nodes. The possibility of chronic fatigue syndrome should be considered in patients with the above symptoms, if they persist for more than 6 months. In this review, we wanted to focus on the possibilities to minimize the symptoms of chronic fatigue syndrome through nutritional and dietary intervention. Materials and methods: Analysis of articles in the EBSCO and Google Scholar database using keywords: Chronic Fatique Syndrome, nutritional, dietary interventions, treatment. Results: Patients with chronic fatigue syndrome suffer from chronic fatigue and not specific symptoms, which makes diagnosis difficult. The analysis of articles shows that dietary and nutritional interventions tailored to the patient reduce the feeling of fatigue, which is the main problem among patients with chronic fatigue syndrome. Positive effects in the form of alleviation of symptoms have been observed while using, inter alia: polyphenols, L-carnitine, probiotics, CoQ10 and NADH and GAA. Conclusions: Dietary and nutritional intervention has a positive effect on intestinal microflora, intestinal mucosa, oxidative stress and proper functioning of mitochondria, thanks to which it reduces symptoms of chronic fatigue syndrome. Individual and appropriate supplementation depending on the etiology of the syndrome can lead to relief of symptoms. Key words: Chronic Fatigue Syndrome, nutritional, dietary interventions, treatment