Vitex negundo Linn commonly known as five leaved chaste tree in English, Nirgudi in Marathi, nirgundi in hindi and indrani in Sanskrit, which have great medicinal value. The present study was done developed extraction method. Microwave extraction and conventional extraction was carried out and both the extracts were compared with their percent of extraction, phytochemical constituent, physicochemical properties and by UV-Vis spectra. Four new parameters were introduced that is bulk density, tapped density, carr’s index and housner’s ratio which was previously not reported. It is observed that microwave and conventional extraction gives different results. This may be due to difference in energy supply for both the extract. Keywords: Vitex nirgundo, Phytochemical, Physicochemical, Microwave extraction, Bulk density, tapped density.