Objective: To estimate the prevalence, risk factor and mechanism of Anterior Cruciate Ligament Injury among Makkah city, Saudi Arabia. Design and Setting: A survey reviews the prevalence and the mechanisms of anterior cruciate ligament (ACL) injury. We used a multiple questionnaire, carry out a 266 from the population were interviewed about the events surrounding their ACL injury. Results: The most common injury of ACL was sport (n = 181). ACL injury occurred due to a sudden increase in running (n=18) and due to stop running suddenly ( n=20) .four-teen of them did not report whether their injury occurred in a practice or in a game. Sixteen were listed as road traffic accident and 14 as related to their work. Noncontact mechanisms were classified as sudden deceleration prior to a change of direction or landing motion. here was the rate of anterior cruciate ligament injury higher in men in compare to the women during the study period. Men\'s football is a high-risk sport for anterior cruciate ligament injury. Unlike running, basketball, volleyball and gymnastics, The level of allowed contact in pivoting sports may be a factor in determining sport-specific anterior cruciate ligament risk. Conclusions: We though that ACL tear is not uncommon in Makkah city population, although ACL still more common in male and in contact injury specially in football player. however protein diet and rehabilitation after surgery shown significance improvement in compare with patient not follow diet and rehabilitation.