This research highlights the study of personnel performance and organizational commitment in university hospitals from northeastern Mexico. Professional health personnel plays an important role in the hospital environment and is an essential issue for the organizational results, as attention is given to the study of organizational factors and individual perceptions that influence organizational behavior such as job satisfaction. The investigation seeks to identify organizational factors that determine personnel performance and organizational commitment through professional health personnel behavioral features, using structural equation modeling based on partial least squares regressions. The analysis developed by the SmartPLS 3 software reveals interesting results that refute what previous research exhibit.