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A Simple, rapid, stability indicating HPTLC method has been developed for estimation of bepotastine besilate. HPTLC separation was carried out on Merck TLC aluminium sheets precoated with silica gel 60F254 using mobile phase as chloroform : methanol. Bepotastine besilate gave sharp peak at RF 0.53 ±0.03 at 225nm.calibration curve was linear in range 5-25ug/band for bepotastine besilate. Stress degradation study was carried out according to ICH guidelines Q1A (R2) and the method was validated as per ICH guideline.
STABILITY INDICATING CHROMATOGRAPHIC METHOD FOR ESTIMATION OF BEPOTASTINE BESILATE
STABILITY INDICATING CHROMATOGRAPHIC METHOD FOR ESTIMATION OF BEPOTASTINE BESILATE
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