AbstractAim: To evaluate the impact of thyroid disorders on the health of both fetus and the mother during pregnancy.Material and Methods: This observational study was conducted in the Department of Obstetrics andGynaecology, NMCH Patna, Bihar, India for one year. We recruited 294 antenatal women in third trimesteradmitted into the obstetric ward with singleton pregnancy for other obstetric indications. Informed consent wasobtained from all subjects. Subjects were chosen irrespective of age, parity, residence and socioeconomic status.Women with multiple pregnancies, a known case of thyroid disorder, on any treatment or with any pre-existingmedical disorder, such as diabetes mellitus, or cardiac or pulmonary disease were excluded. Routinehematological parameters and estimation of T3, T4 and TSH was conducted. Patients with a deranged thyroidprofile were subsequently assessed for maternal and fetal complications. Infertility, family history of thyroiddisorder, menstrual history, recurrent abortions, mean T3, T4, TSH levels, haemoglobin levels, maternal and fetaloutcome were the main study variables.Results: Of the 294 women screened, 46 (15.64%) had abnormal thyroid function. Prevalence of subclinicalhypothyroidism, overt hypothyroidism, and subclinical hyperthyroidism was 7.48% (n = 22), 5.10% (n = 15), and3.06% (n = 9), respectively demonstrating that the occurrence of subclinical hypothyroidism is more commonduring pregnancy. Of the 46 women with dysfunction, 23.91% had a history of irregular menstrual rhythm; 4.34%had history of infertility treatment; 4.34% had family history of thyroid disorder and 4.34% had history ofrecurrent miscarriage. There was no statistically significant association between any of these factors and theoccurrence of thyroid disorder (p values were 0.655, 0.217, 0.079, and 0.752, respectively).Conclusion: Association of maternal anemia, preeclampsia, increased cesarean delivery, presence of LBWbabies, low Apgar score and increased number of NICU admission; is a major finding of this study

AbstractAim: To evaluate the impact of thyroid disorders on the health of both fetus and the mother during pregnancy.Material and Methods: This observational study was conducted in the Department of Obstetrics andGynaecology, NMCH Patna, Bihar, India for one year. We recruited 294 antenatal women in third trimesteradmitted into the obstetric ward with singleton pregnancy for other obstetric indications. Informed consent wasobtained from all subjects. Subjects were chosen irrespective of age, parity, residence and socioeconomic status.Women with multiple pregnancies, a known case of thyroid disorder, on any treatment or with any pre-existingmedical disorder, such as diabetes mellitus, or cardiac or pulmonary disease were excluded. Routinehematological parameters and estimation of T3, T4 and TSH was conducted. Patients with a deranged thyroidprofile were subsequently assessed for maternal and fetal complications. Infertility, family history of thyroiddisorder, menstrual history, recurrent abortions, mean T3, T4, TSH levels, haemoglobin levels, maternal and fetaloutcome were the main study variables.Results: Of the 294 women screened, 46 (15.64%) had abnormal thyroid function. Prevalence of subclinicalhypothyroidism, overt hypothyroidism, and subclinical hyperthyroidism was 7.48% (n = 22), 5.10% (n = 15), and3.06% (n = 9), respectively demonstrating that the occurrence of subclinical hypothyroidism is more commonduring pregnancy. Of the 46 women with dysfunction, 23.91% had a history of irregular menstrual rhythm; 4.34%had history of infertility treatment; 4.34% had family history of thyroid disorder and 4.34% had history ofrecurrent miscarriage. There was no statistically significant association between any of these factors and theoccurrence of thyroid disorder (p values were 0.655, 0.217, 0.079, and 0.752, respectively).Conclusion: Association of maternal anemia, preeclampsia, increased cesarean delivery, presence of LBWbabies, low Apgar score and increased number of NICU admission; is a major finding of this study