Aim: The aim of the present study was to compare the efficacy and safety of 25 mcg of fentanyl vs 5 mcg dexmedetomidine as an adjuvant in 0.5% of 2.5 ml of isobaric levobupivacaine in lower limb orthopaedic surgery. Methods: The present study was conducted in the Department of Anesthesiology, Jawaharlal Nehru Medical College & Hospital, Bhagalpur, Bihar, India. The study participants were randomly divided into three groups. The study population consisted of 90 adult patients who were classified as American Society of Anesthesiologists (ASA) physical status I or II, undergoing elective lower limb orthopaedic surgery under spinal anesthesia. Results: In the present study, male dominated in all the three groups as compared to females. The patients were more in ASA I as compared to ASA II. The mean time for onset of sensory block was 11.04 ±4.21 min in the saline group and 8.76±2.99 min in the dexmedetomidine group and 2.28±1.42 min in the fentanyl group. The mean time taken to achieve maximum sensory block in group A was 16.18±4.83 min, in group D was 14.16±3.42 min and in group F it was 5.52±1.67 min so maximum sensory block was achieved earlier in group. Peak level of sensory block attained in the fentanyl group was T4 and the peak level of sensory block in dexmedetomidine group was T6 and in the saline group peak level was T8. Conclusion: Dexmedetomidine group has longer onset of and duration of sensory block and effective postoperative analgesia and fewer side effect as compared to fentanyl group.

Aim: The aim of the present study was to compare the efficacy and safety of 25 mcg of fentanyl vs 5 mcg dexmedetomidine as an adjuvant in 0.5% of 2.5 ml of isobaric levobupivacaine in lower limb orthopaedic surgery. Methods: The present study was conducted in the Department of Anesthesiology, Jawaharlal Nehru Medical College & Hospital, Bhagalpur, Bihar, India. The study participants were randomly divided into three groups. The study population consisted of 90 adult patients who were classified as American Society of Anesthesiologists (ASA) physical status I or II, undergoing elective lower limb orthopaedic surgery under spinal anesthesia. Results: In the present study, male dominated in all the three groups as compared to females. The patients were more in ASA I as compared to ASA II. The mean time for onset of sensory block was 11.04 ±4.21 min in the saline group and 8.76±2.99 min in the dexmedetomidine group and 2.28±1.42 min in the fentanyl group. The mean time taken to achieve maximum sensory block in group A was 16.18±4.83 min, in group D was 14.16±3.42 min and in group F it was 5.52±1.67 min so maximum sensory block was achieved earlier in group. Peak level of sensory block attained in the fentanyl group was T4 and the peak level of sensory block in dexmedetomidine group was T6 and in the saline group peak level was T8. Conclusion: Dexmedetomidine group has longer onset of and duration of sensory block and effective postoperative analgesia and fewer side effect as compared to fentanyl group.