AbstractAim: The aim of the present study was to identify various factors contributing to failure of medical managementin patients with chronic rhinosinusitis.Methods: This was a Prospective observational study with sample size of 50 conducted in the Department ofENT, Nalanda medical college and Hospital, Patna, Bihar, India. Patients above the age of 15 years and below theage of 65years, with regular follow up and not on any steroids for last one month were included in to this study.Results: Diagnostic Nasal endoscopy revealed that DNS was the most common finding in both groups withhighest incidence in group B, followed by Mucin and Middle turbinate hypertrophy. Among these, Deviated nasalseptum and Mucin were high in non-responders comparatively and is significant statistically. Non ContrastComputed tomography of nose and paranasal sinuses showed statistically significant result (p<0.05).In our study,Fungus was seen more in group B but was statistically insignificant. Immunocompromised status was more ingroup B which was statistically significant (p <0.05).Conclusion: The study emphasized that presence of Deviated nasal septum, Mucin, Aspergillus niger andcompromissed immune status contributed for failure of medical management in chronic rhinosinusitis

AbstractAim: The aim of the present study was to identify various factors contributing to failure of medical managementin patients with chronic rhinosinusitis.Methods: This was a Prospective observational study with sample size of 50 conducted in the Department ofENT, Nalanda medical college and Hospital, Patna, Bihar, India. Patients above the age of 15 years and below theage of 65years, with regular follow up and not on any steroids for last one month were included in to this study.Results: Diagnostic Nasal endoscopy revealed that DNS was the most common finding in both groups withhighest incidence in group B, followed by Mucin and Middle turbinate hypertrophy. Among these, Deviated nasalseptum and Mucin were high in non-responders comparatively and is significant statistically. Non ContrastComputed tomography of nose and paranasal sinuses showed statistically significant result (p<0.05).In our study,Fungus was seen more in group B but was statistically insignificant. Immunocompromised status was more ingroup B which was statistically significant (p <0.05).Conclusion: The study emphasized that presence of Deviated nasal septum, Mucin, Aspergillus niger andcompromissed immune status contributed for failure of medical management in chronic rhinosinusitis