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ZENODO
Article . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
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Role of Platelet Rich Plasma in Treatment of Chronic Achilles Tendinopathy

Authors: Saurabh Singh; Rohit Patel; Vaibhav Adhaulia; Chandra Shekhar Verma; Dibya Singh; Garima Yadav; Rahul Patel;

Role of Platelet Rich Plasma in Treatment of Chronic Achilles Tendinopathy

Abstract

Introduction: It is thought that Achilles tendopathy is related to sports activities, but it is more often found in people who do not involved in sports. The biggest cause is the excessive overburdening of the tendon. At present most of the systematic review and metanalysis shows that the role of PRP in tendinopathy is insignificant. Aims and Objectives: This study focuses on Leucocyte-rich platelet rich plasma for treatment of chronic achilles tendinopathy in terms of patient reported VAS score, VISA-A Score. This work also measures tendon thickness and intratendinous vascularity by USG & Doppler study. Methodology and Results: This was a Prospective longitudinal Study/case series. Patients were injected with leucocyte rich platelet rich plasma in Achilles tendon and evaluated on 6, 12, 18 weeks postinjection. In our result VISA-A score shows improvement in initial 6 weeks then slight rise upto 18 weeks with p value of <0.001. VAS score shows initial sudden decline upto 6 week then gradual decline in score with p value of <0.001. Tendon thickness decreased in significant number of patients (80.64% patients) at 18 weeks with p value <0.001. Sudden decrease in tendon vascularity (80.64% of patients) was seen at 12 weeks (p<0.001). Conclusion: At present ongoing work in form of case series, case reports and some randomized control trials shows benificial role of PRP in Achilles tendinopathy in terms of functional / radiological / histopathological outcome indicating that further research required in field of dose and frequency of PRP administration, standardization of PRP prepration, role of adding other biologics, long term radiological / histological follow up combined with functional outcome.

Introduction: It is thought that Achilles tendopathy is related to sports activities, but it is more often found in people who do not involved in sports. The biggest cause is the excessive overburdening of the tendon. At present most of the systematic review and metanalysis shows that the role of PRP in tendinopathy is insignificant. Aims and Objectives: This study focuses on Leucocyte-rich platelet rich plasma for treatment of chronic achilles tendinopathy in terms of patient reported VAS score, VISA-A Score. This work also measures tendon thickness and intratendinous vascularity by USG & Doppler study. Methodology and Results: This was a Prospective longitudinal Study/case series. Patients were injected with leucocyte rich platelet rich plasma in Achilles tendon and evaluated on 6, 12, 18 weeks postinjection. In our result VISA-A score shows improvement in initial 6 weeks then slight rise upto 18 weeks with p value of <0.001. VAS score shows initial sudden decline upto 6 week then gradual decline in score with p value of <0.001. Tendon thickness decreased in significant number of patients (80.64% patients) at 18 weeks with p value <0.001. Sudden decrease in tendon vascularity (80.64% of patients) was seen at 12 weeks (p<0.001). Conclusion: At present ongoing work in form of case series, case reports and some randomized control trials shows benificial role of PRP in Achilles tendinopathy in terms of functional / radiological / histopathological outcome indicating that further research required in field of dose and frequency of PRP administration, standardization of PRP prepration, role of adding other biologics, long term radiological / histological follow up combined with functional outcome.

Keywords

Achilles Tendinopathy, Platelet Rich Plasma, VISA-A Score, VAS Score, Achilles Tendon Thickness and Vascularity

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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