Background: Cervical cancer is a leading cause of AIDS-defining illness, and HIV-positive women worldwide. Detection of cervical cancer in precancerous stage is 100% curable. Aim: To determine the rate of cervical screening among HIV-positive women and compare the performance of screening tests and assesses factors affecting participation. Methods: HIV-positive women aged 30–59 years attend the anti-retroviral therapy (ART) clinics were screened by conventional Pap, HPV testing (Hybrid Capture 2) and visual inspection with acetic acid (VIA). A cohort of HIV-negative women from the community matched for age and parity were screened similarly. Screen-positive women underwent colposcopy and biopsy. Factors affecting participation were assessed. Results: Out of total cases majority of them (44.4%) belonged to 30-39 years age group. Most of the participants (96.8%) were unaware about cervical screening, 97.2% were housewives and 74.4% belonged to upper lower socio-economic status. The mean parity of was 2.15±1.29 and maximum (69.2%) females were multiparous. Conventional smear and LBC revealed concordant findings in 16.7%, 100%, 85.7% and 100% cases of ASCUS, LSIL, HSIL and SCC respectively (p<0.05). Among the screening methods, sensitivity and negative predictive value was 100% for detection of abnormal cytology for liquid-based cytology whereas VILI had highest specificity. Overall, diagnostic accuracy was highest for liquid-based cytology. Conclusion: Risk of cervical cancer was higher in HIV infected women. Frequent screening of these patients for cervical cancer can reduces the morbidity and mortality among women.

Background: Cervical cancer is a leading cause of AIDS-defining illness, and HIV-positive women worldwide. Detection of cervical cancer in precancerous stage is 100% curable. Aim: To determine the rate of cervical screening among HIV-positive women and compare the performance of screening tests and assesses factors affecting participation. Methods: HIV-positive women aged 30–59 years attend the anti-retroviral therapy (ART) clinics were screened by conventional Pap, HPV testing (Hybrid Capture 2) and visual inspection with acetic acid (VIA). A cohort of HIV-negative women from the community matched for age and parity were screened similarly. Screen-positive women underwent colposcopy and biopsy. Factors affecting participation were assessed. Results: Out of total cases majority of them (44.4%) belonged to 30-39 years age group. Most of the participants (96.8%) were unaware about cervical screening, 97.2% were housewives and 74.4% belonged to upper lower socio-economic status. The mean parity of was 2.15±1.29 and maximum (69.2%) females were multiparous. Conventional smear and LBC revealed concordant findings in 16.7%, 100%, 85.7% and 100% cases of ASCUS, LSIL, HSIL and SCC respectively (p<0.05). Among the screening methods, sensitivity and negative predictive value was 100% for detection of abnormal cytology for liquid-based cytology whereas VILI had highest specificity. Overall, diagnostic accuracy was highest for liquid-based cytology. Conclusion: Risk of cervical cancer was higher in HIV infected women. Frequent screening of these patients for cervical cancer can reduces the morbidity and mortality among women.