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ZENODO
Dataset . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Dataset . 2024
License: CC BY
Data sources: Datacite
ZENODO
Dataset . 2024
License: CC BY
Data sources: Datacite
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Gene-collapsing analysis of clonal haematopoiesis in 136,401 Admixed Americans and 416,118 Europeans

Research datakeyboard_double_arrow_right Dataset 08 Jul 2024Publisher:Zenodo
Authors: Wen, Sean; Kuri-Morales, Pablo; Hu, Fengyuan; Nag, Abhishek; Tachmazidou, Ioanna; Deevi, Sri V. V.; Taiy, Haeyam; +18 Authors

doi: 10.5281/zenodo.12691572 , 10.5281/zenodo.12691571

Gene-collapsing analysis of clonal haematopoiesis in 136,401 Admixed Americans and 416,118 Europeans

Abstract

We performed gene-collapsing (gene burden) analysis of germline genetic variants identified from whole-exome sequencing (WES) to identify novel inherited genetic determinants of clonal haematopoiesis (CH). Here, we provide the summary statistics from CH gene-collapsing analysis performed on Admixed Americans recruited to the Mexico City Prospective Study (MCPS), Europeans recruited to the United Kingdom Biobank (UKB), and cross-ancestry meta-analysis of Admixed Americans and Europeans. Analyses was performed with Fisher's exact test (for MCPS and UKB analysis) and Cochran–Mantel–Haenszel test (for meta-analysis).

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average