A chemical is considered hazardous when it poses a risk of harm in a certain setting or circumstance. Industrial hazards are a major occupational health and safety (OHS) concern in the pharmaceutical manufacturing sector. The pharmaceutical industry, which is involved in the research, development, manufacturing, and marketing of medicines for the health of humans and animals, is an essential part of healthcare systems around the worldwide . Like other chemical sectors, the pharmaceutical industry faces numerous environmental challenges. The scientific creation, investigation, and development of medications—that is, substances useful in the prevention or treatment of diseases and disorders—forms the foundation of the pharmaceutical industry. The formulation and production of APIs call for the use of a wide variety of chemicals, some of which are corrosive and irritating agents like acids, bases, oxidizing and reducing agents, solvents, and many more. These chemicals can occasionally be found in very high concentrations and pose a health risk to those who perform the various processes. The ethical and regulatory requirements of numerous statutes that regulate the pharmaceutical industry's operations demand that the chemical risks associated with handling these agents be effectively managed for the sake of the industry's workers' safety. This article provides an in-depth look at the various chemical threats that the pharmaceutical industry typically faces, as well as how these threats are managed and regulated in India.