Background: Pancreatitis by itself is a disease, which is unique, protean and extrudes into the diagnostic arena. Acute pancreatitis (AP) is an acute inflammatory process of the pancreas with variable involvement Cardiovascular and pulmonary system. Methods: The study was conduct in the Department of medicine J.L.N. Medical College & Hospitals, Ajmer. After taking informed consent eligible acute pancreatitis patients were enrolled according to the inclusion and exclusion criteria. Result: In our study, maximum patients (96.00%) were male and (80%) were from 31-50 years of age group. Patients with CTSI ≥7 (severe pancreatitis) had significantly higher CRP score of 125.29±6.84 mg/dl. positive S. CRP Value were present with sensitivity 100% and specificity 16.13%. The mean CKMB was found to be 33.52 ± 19.51 IU/L. and in Patients with CTSI ≥7 (severe pancreatitis) was 52.57±26.97 IU/l. In case of severe pancreatitis positive CKMB value were present with sensitivity 85.71% and specificity 51.61%. Abnormal ECG changes were seen in 42% patients (42/100), all patients had Sinus tachycardia. Abnormal ECG finding were present with sensitivity 100% and specificity 62.37%. 20% of the studied patients, were found to be having abnormalities in 2D echo and mostly have diastolic dysfunction. Conclusion: In our study association of high S. CRP and S. CKMB levels with severe Pancreatitis had high sensitivity. Association of 2D ECHO abnormalities with severe pancreatitis was highly specific. Association of ECG changes with Severe pancreatitis had 100% sensitivity. Most common ECG abnormalities was sinus tachycardia.

Background: Pancreatitis by itself is a disease, which is unique, protean and extrudes into the diagnostic arena. Acute pancreatitis (AP) is an acute inflammatory process of the pancreas with variable involvement Cardiovascular and pulmonary system. Methods: The study was conduct in the Department of medicine J.L.N. Medical College & Hospitals, Ajmer. After taking informed consent eligible acute pancreatitis patients were enrolled according to the inclusion and exclusion criteria. Result: In our study, maximum patients (96.00%) were male and (80%) were from 31-50 years of age group. Patients with CTSI ≥7 (severe pancreatitis) had significantly higher CRP score of 125.29±6.84 mg/dl. positive S. CRP Value were present with sensitivity 100% and specificity 16.13%. The mean CKMB was found to be 33.52 ± 19.51 IU/L. and in Patients with CTSI ≥7 (severe pancreatitis) was 52.57±26.97 IU/l. In case of severe pancreatitis positive CKMB value were present with sensitivity 85.71% and specificity 51.61%. Abnormal ECG changes were seen in 42% patients (42/100), all patients had Sinus tachycardia. Abnormal ECG finding were present with sensitivity 100% and specificity 62.37%. 20% of the studied patients, were found to be having abnormalities in 2D echo and mostly have diastolic dysfunction. Conclusion: In our study association of high S. CRP and S. CKMB levels with severe Pancreatitis had high sensitivity. Association of 2D ECHO abnormalities with severe pancreatitis was highly specific. Association of ECG changes with Severe pancreatitis had 100% sensitivity. Most common ECG abnormalities was sinus tachycardia.