A series of morpholine mannich base derivatives were synthesized by a single step reaction of morpholine with substitutedbenzaldehydes and N-phenylacetamide. Progress of reaction was monitored by TLC using ethylacetate and n-hexane asmobile phase. The compounds were characterized by ATR and 1HNMR spectral analysis. Antioxidant assay of thesynthesized compounds was done by DPPH and ABTS assay method using Ascorbic acid as standard. The synthesizedmorpholine mannich base derivatives demonstrated significant radical scavenging property.

A series of morpholine mannich base derivatives were synthesized by a single step reaction of morpholine with substitutedbenzaldehydes and N-phenylacetamide. Progress of reaction was monitored by TLC using ethylacetate and n-hexane asmobile phase. The compounds were characterized by ATR and 1HNMR spectral analysis. Antioxidant assay of thesynthesized compounds was done by DPPH and ABTS assay method using Ascorbic acid as standard. The synthesizedmorpholine mannich base derivatives demonstrated significant radical scavenging property.