Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Article . 2023
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2023
License: CC BY
Data sources: Datacite
ZENODO
Article . 2023
License: CC BY
Data sources: Datacite
versions View all 2 versions
addClaim

Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad

Authors: Radha M; Keerthana Muppidi; Pooja Shivkumar; Divya L;

Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad

Abstract

Background: Papulosquamous disorders, characterised by scaly papules and plaques are one of the most common skin dermatoses seen by dermatologists. Some of the examples of papulosquamous skin disorders include lichen planus, psoriasis, pityriasis rosea, pityriasis rubra pilaris, parapsorias etc. Due to clinical and morphological overlap, it is sometimes difficult to make a straight forward clinical diagnosis without histological confirmation. Some of the histopathological features are specific and characteristic for each entity. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis. Aims and Objectives: The present study aims to analyse various histopathological patterns of papulosquamous lesions of the skin based on the tissue reaction pattern and assess the concordance of provisional clinical diagnosis and histopathological diagnosis. Materials And Methods: This is a hospital based retrospective study of 2 year duration from 2021-2022, at Department of pathology. Descriptive data on clinical history and histopathological examination of all the cases of papulosquamous lesions of skin was collected and results were drawn on various parameters using statistical analysis tools. Results: Out of total 90 cases of clinically suspicious papulosquamous disorders, only 74 cases confirmed as various papulosquamous disorders histopathologically with a positive correlation of 82.2 % and negative correlation of 17.7%. Majority (23 cases) were in the age group of 31 to 40 years. There was slight male preponderance with male: female ratio being 1.14:1.The commonest diagnosis was Lichen planus and its variants (23 cases), followed by Psoriasis and its variants (19 cases), eczema (17 cases),pityriasis rosea (5 cases), Lichen nitidus (3cases), Lichenoid dermatitis (3 cases), Parapsoriasis (2 cases), 1 case each of pityriasis rubra pilaris and chronic cutaneous lupus. Conclusion: The present study is designed to know the correlation between the clinical patterns of various papulosquamous disorders and their histopathological diagnosis .There are many studies done on clinical correlation with histopathological diagnosis but still the positive correlation is not reaching up to 100%, some studies have negative correlation of around 40%. Therefore, more studies are required in this field to appropriately diagnose and manage the papulosquamous disorders in order to reduce the disease burden and as a key to better patient care.

Background: Papulosquamous disorders, characterised by scaly papules and plaques are one of the most common skin dermatoses seen by dermatologists. Some of the examples of papulosquamous skin disorders include lichen planus, psoriasis, pityriasis rosea, pityriasis rubra pilaris, parapsorias etc. Due to clinical and morphological overlap, it is sometimes difficult to make a straight forward clinical diagnosis without histological confirmation. Some of the histopathological features are specific and characteristic for each entity. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis. Aims and Objectives: The present study aims to analyse various histopathological patterns of papulosquamous lesions of the skin based on the tissue reaction pattern and assess the concordance of provisional clinical diagnosis and histopathological diagnosis. Materials And Methods: This is a hospital based retrospective study of 2 year duration from 2021-2022, at Department of pathology. Descriptive data on clinical history and histopathological examination of all the cases of papulosquamous lesions of skin was collected and results were drawn on various parameters using statistical analysis tools. Results: Out of total 90 cases of clinically suspicious papulosquamous disorders, only 74 cases confirmed as various papulosquamous disorders histopathologically with a positive correlation of 82.2 % and negative correlation of 17.7%. Majority (23 cases) were in the age group of 31 to 40 years. There was slight male preponderance with male: female ratio being 1.14:1.The commonest diagnosis was Lichen planus and its variants (23 cases), followed by Psoriasis and its variants (19 cases), eczema (17 cases),pityriasis rosea (5 cases), Lichen nitidus (3cases), Lichenoid dermatitis (3 cases), Parapsoriasis (2 cases), 1 case each of pityriasis rubra pilaris and chronic cutaneous lupus. Conclusion: The present study is designed to know the correlation between the clinical patterns of various papulosquamous disorders and their histopathological diagnosis .There are many studies done on clinical correlation with histopathological diagnosis but still the positive correlation is not reaching up to 100%, some studies have negative correlation of around 40%. Therefore, more studies are required in this field to appropriately diagnose and manage the papulosquamous disorders in order to reduce the disease burden and as a key to better patient care.

Related Organizations
Keywords

Papulosquamous disorders, clinical data, Clinico-histopathological correlation

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Related to Research communities