This deposit contains all the single-molecule trajectories reported in "The glucocorticoid receptor potentiates aldosterone-induced transcription by the mineralocorticoid receptor". To access the tracks, open the mat file in MATLAB. This contains a MATLAB table with the following fields: summary_table.cell_protein{i} identifies the ith dataset i.e. cell line + protein + treatment. summary_table.X{i}{j} is an Nx2 array of x and y coordinates (in microns) for track j in condition i. N is the number of localizations in that track. Time interval between localizations is 200 ms. Details on data acquisition and tracking parameters can be found in the associated manuscript.