This dataset concerns pathology samples taken from patients at doctors’ offices (i.e., GPs’ surgeries) in and around the Southampton area. Vans collect these samples and transport them to a pathology laboratory at Southampton General Hospital for analysis. The data detail where and when samples were generated, and the van routes used to transport them. The locations of places in the dataset are representative of the real-world situation, but have been altered so as to be fictitious and do not describe actual activity.