AbstractAim: The aim of the study was to determine histopathological features of different subtypes of carcinoma breastand correlate with the presence of proliferative lesions of breast in peritumoral area.Methods: This Observational study was conducted for a period of 1 year at department of Pathology,Darbhanga Medical College and Hospital, Darbhanga, Bihar, India and A total of 100 cases that satisfied theinclusion criteria were included in this study. Specimens were received in 10% Formalin. Clinical details, grossfindings including tumor size were noted.Results: Age group of patients included in the study ranges between 32 to 76 years with a mean age of 54 years.Majority of the patients belonged to 51 to 60 years seen in 35 (35%) cases. 44 (44%) cases belonged topostmenopausal age group, 37 (37%) and 17(20%) belonged to perimenopausal and premenopausal age grouprespectively. In the present study, 55 (55%) of tumors were located at the right side, 45 (45%) at the left sidebreast. None of the patients had bilateral carcinoma. Of the 100 cases included in the present study 82 (82%)were Invasive Ductal Carcinoma of No Special Type (IDC NST). Most common findings in peritumoral area ofbreast were non proliferative epithelial lesions 53 (53%).Conclusion: The present study concluded that non-proliferative breast lesions were the most predominanthistological lesion in peritumoral area. Histopathological examination of peritumoral area in mastectomyspecimens is a simple and valuable method that helps to stratify the risk of carcinoma in contralateral breast.

AbstractAim: The aim of the study was to determine histopathological features of different subtypes of carcinoma breastand correlate with the presence of proliferative lesions of breast in peritumoral area.Methods: This Observational study was conducted for a period of 1 year at department of Pathology,Darbhanga Medical College and Hospital, Darbhanga, Bihar, India and A total of 100 cases that satisfied theinclusion criteria were included in this study. Specimens were received in 10% Formalin. Clinical details, grossfindings including tumor size were noted.Results: Age group of patients included in the study ranges between 32 to 76 years with a mean age of 54 years.Majority of the patients belonged to 51 to 60 years seen in 35 (35%) cases. 44 (44%) cases belonged topostmenopausal age group, 37 (37%) and 17(20%) belonged to perimenopausal and premenopausal age grouprespectively. In the present study, 55 (55%) of tumors were located at the right side, 45 (45%) at the left sidebreast. None of the patients had bilateral carcinoma. Of the 100 cases included in the present study 82 (82%)were Invasive Ductal Carcinoma of No Special Type (IDC NST). Most common findings in peritumoral area ofbreast were non proliferative epithelial lesions 53 (53%).Conclusion: The present study concluded that non-proliferative breast lesions were the most predominanthistological lesion in peritumoral area. Histopathological examination of peritumoral area in mastectomyspecimens is a simple and valuable method that helps to stratify the risk of carcinoma in contralateral breast.