NP-KG is a biomedical knowledge graph (KG) to identify and generate mechanistic hypotheses for pharmacokinetic natural product-drug interactions (NPDIs). NP-KG uses the PheKnowLator ecosystem to create an ontology-grounded KG. It then uses two relation extraction systems to extract triples from natural product-related biomedical literature to create a literature-based graph, and integrates the nodes and edges in the ontology-grounded KG. See GitHub repository for more details and instructions: https://github.com/sanyabt/np-kg. File Descriptions for version 3: I. NP-KG Merged TSV format NP-KG_v3.0.0.tsv - Merged KG with ontology-grounded KG and literature-based graph as TSV file nodeLabels_v3.0.0.tsv nodeTypes_v3.0.0.tsv II. NP-KG Merged gpickle format NP-KG_v3.0.0.gpickle - Merged KG with ontology-grounded KG and literature-based graph as NetworkX multidigraph object. nodeLabels_v3.0.0.pickle - Node labels for all nodes in the KG in dictionary format.

Supporting Grant - National Institutes of Health National Center for Complementary and Integrative Health Grant U54 AT008909