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ZENODO
Article . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
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Predpoveď kardiovaskulárneho rizika pomocou hmotnostnej spektrometrie

Cardiovascular risk prediction using mass spectrometry
Authors: Turay, Jozef;

Predpoveď kardiovaskulárneho rizika pomocou hmotnostnej spektrometrie

Abstract

Súhrn Lipidomika je vedný obor, ktorý sa zaoberá štúdiom biochemických dráh lipidov v biologických systémoch. Ide o novú subšpecializáciu klinickej biochémie, ktorá je podložená výsledkami najmä hmotnostnej spektrometrie. V poslednom desaťročí sa nahromadili dôkazy o úlohe ceramidov a fosfolipidov ako možných mediátorov ateroklerózou podmienených kardiovaskulárnych ochorení (ASKVO) alebo prognostických biomarkerov. Kombinácia plazmatickej hladiny ceramidov a fosfolipidov zlepšuje predpoveď ASKVO. CERT1 a CERT2 sú nové skórovacie systémy v predpovedi koronárneho rizika na základe stanovenia špecifických ceramidov a fosfolipidov hmotnostnou spektrometriou. Kľúčové slová: ceramidy; fosfolipidy; hmotnostná spektrometria; skórovací systém; ateroskleróza; kardiovaskulárne ochorenie Abstract Lipidomics is the branch of science that deals with the study of the biochemical pathways of lipids in biological systems. Lipidomics is a new sub-specialty of clinical biochemistry using mainly mass spectrometry. In the last decade, evidence has accumulated for the role of ceramides and phospholipids as possible mediators of atherosclerosis-related cardiovascular disease (ARVD) or prognostic biomarkers. The combination of plasma ceramide and phospholipid levels improves the prediction of ASKVO events. CERT1 and CERT 2 are novel scoring systems in the prediction of coronary risk based on the determination of specific ceramides and phospholipids by mass spectrometry. Key words: ceramides; phospholipids; mass spectrometry; scoring system; atherosclerosis; cardiovascular disease

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average