In Medical Science, the methods of topological descriptor computation can help to obtain the available pharmacological, biological, chemical and medical information of drugs. So that the connectivity indices are applied to measure the chemical characteristics of drugs. In this paper, we introduce the atom bond connectivity Revan index and geometric-arithmetic Revan indices of a molecular graph. Furthermore, we determine the sum connectivity Revan index, atom bond connectivity Revan index and geometric-arithmetic Revan index of chemically interesting drugs like jagged-rectangle benzenoid systems and polycyclic aromatic hydrocarbons.