The replacement of single anterior teeth by means of endosseous implants implies the achievement of success in restoring both aesthetic and function. Dental implants are established substitutes for replacing missing teeth. For the successful implant placement, the volume of adequate bone at the recipient site is absolutely essential. Peri-implant dehiscence defects are most often encountered at the site of implant placement that requires bone augmentation. These defects may range from very small lack of marginal bone to large areas of denuded implant surfaces. Recent clinical studies have demonstrated that the application of various bone grafts in conjunction with placement of implants leads to successful coverage of the previously exposed implant surfaces. The present case report highlights the bone augmentation of the peri-implant dehiscence defect by novel Calcium phosphosilicate, Hydroxyapatite with collagen bone graft and GBR membrane while performing the first-stage implant surgery for a single edentulous area.