The study evaluated the Cyberpreneurship and Economic Development of Small and Medium Enterprises’ (SMEs) in Enugu State. The specific objectives consequently were to: evaluate the relationship of audio-video technicians on unemployment rates and ascertain the relationship of IT professionals on the income generation in Enugu State. The area of the study was selected SMEs of ICT centres in Enugu state. The study used the descriptive survey design approach. The primary source of data was the administration of questionnaire. A total population of 114 staff was used. The whole population was used due to small number. Eighty six (86) staff returned the questionnaire and accurately filled. Data was presented and analyzed using Likert Scale and the hypotheses using Pearson correlation coefficient (r). The findings indicated Audio-video technicians had significant positive relationship on employment rates in Enugu State, Z (95, n = 211), 2.911 < 3.936 = p. < 0.05 and IT professionals had significant positive relationship on the income generation in Enugu State, Z (95,n = 86), 2.696 < 4.367 = p. < 0.05. The study concluded that Audio-video technicians and IT professionals had significant positive effect on employment rates and income generation in Enugu State. The study recommended amongst others that the unemployed or youths should avail themselves the opportunity of equipping themselves with Cyberpreneurship skills that enhance the use of the internet in marketing of their business.